Latest Dental News

Poor Oral hygiene ‘can trigger clots’
Bugs escaping from the mouth employ a survival trick that can trigger deadly blood clots, research has shown.
The link between bacteria that cause dental plaque and heart disease and strokes is well known. Scientists have now discovered just why it is that the microbes pose a far bigger risk than receding gums.
Once let loose in the bloodstream they deploy a protein that forces platelets to bind together and shield the bugs with clots.

Study leader Professor Howard Jenkinson, from the University of Bristol, said: “When the platelets clump together they completely encase the bacteria. This provides a protective cover not only from the immune system, but also from antibiotics that might be used to treat infection. BBCNEWS
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ITs meeting time- See Dental Meeting Caleder HERE ——–

California Dental Board Exam will change
A bill headed to California Gov. Arnold Schwarzenegger’s desk would change the way examinations are administered to the state’s dental school graduates.

Assembly Bill 1524, Dental Licensure by Hybrid Portfolio Pathway (HPP), which passed both Houses the last week of August, abolishes the clinical and written examination administered by the state dental board. The bill would replace that examination with an assessment process administered while the applicant is enrolled at an in-state dental school. The HPP would utilize uniform standards of minimal clinical experiences and require a final assessment of the submitted portfolio at the end of the school program. LINK
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$600M fine for illegally marketing Botox
Pharmaceutical giant Allergan will pay $600 million to settle civil and criminal accusations that it illegally marketed Botox for uses for which the drug had not been approved.
“The FDA had approved therapeutic uses of Botox for only four rare conditions, yet Allergan made it a top corporate priority to maximize sales of far more lucrative off-label uses that were not approved by FDA,” U.S. Attorney Sally Yates said. “Allergan further demanded tremendous growth in these off-label sales year after year, even when there was little clinical evidence that these uses were effective. The FDA approval process ensures that pharmaceutical companies market their medications for uses that are proven to be effective, and this case demonstrates that companies that fail to comply with these rules face criminal prosecution and stiff penalties.” NEWSLINK

Erbium laser can debond ceramic brackets
AJODO Aug 2010
Researchers from Yeditepe University in Istanbul wanted to develop a new way to debond ceramic brackets by scanning the brackets with an Er:YAG laser.

For their in vitro study, they randomly divided 60 bovine mandibular incisors into two groups of 30. Polycrystalline ceramic brackets were placed on their labial surfaces using an orthodontic composite adhesive (Transbond XT, 3M Unitek) and light cured for 40 seconds.
The control group was not laser scanned. In the other group, Er:YAG laser energy was applied to each bracket at 4.2 W for 9 seconds. The force required for debonding the brackets was applied 45 seconds after laser exposure.
Implant do better-Pre-op prophylactic antibiotics
A Cochrane meta-analysis published online in July concluded that preoperative antibiotics prevent failure of dental implants. Even so, controversy still exists over whether all implant patients should be given prophylactic antibiotics prior to surgery.
When the studies were aggregated by the meta-analysis team — for a total of 1,007 patients — statistical analyses indicated no significant heterogeneity among the studies. The results also showed patients who received antibiotics had a statistically significant 60% reduction in risk of implant failure (95% confidence interval 0.19-0.84). The team calculated that 33 patients needed to be treated with antibiotics to prevent them from having an implant failure.
Dr. Esposito and his colleagues concluded, as they did in their 2008 study and meta-analysis, that routinely administering prophylactic antibiotics is advisable for patients undergoing routine procedures for placement of dental implants. Review concludes “It is still unclear whether postoperative antibiotics are of any additional benefits”.FULL REVIEW

‘High-quality research and a US $1.5 billion industry’
India is emerging as a global hub for clinical research. According to projections from McKinsey & Company, the Indian clinical research industry could attract US $1.5 billion of revenue from U.S. and European sponsors by 2010, creating a demand for more than 10,000 investigators trained in good clinical practice (GCP) and supported by nearly 50,000 clinical research professionals. The revenue expected to be reaching US $ 20 billion in India till 2015.With increased outsourcing from the U.S. and Europe to India, global pharmaceutical companies and Indian entrepreneurs have set up contract research organizations (CROs) in India. They are attracting highly competent professionals, both in the clinical research profession and the knowledge process outsourcing sector.  Link